The viscosity can be accurately determined in the early stage of preparation, which plays a key role in reducing the number of failed candidate samples in the follow-up development stage. It is therefore necessary to monitor the viscosity during the pharmaceutical process to ensure quality control and compliance with the Pharmacopoeia requirements. For example, the viscosity of a semisolid formulation may affect the diffusion rate and release of the drug. The measurement of viscosity is particularly important among the many analytical difficulties faced by researchers in the development of pharmaceutical, especially preformulation development stage of biopharmaceutical.
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